General description
The CD7 antigen is a membrane-bound 40 kDa glycoprotein expressed on thymocytes, mature T cells, a large majority of natural killer cells, pluripotent hematopoietic stem cells, and progenitor cells of lymphoid and myeloid cells (Bowen, 2002 and 1997). CD7 is one of the earliest T-cell-specific antigens to be expressed in lymphocytes, and the only early marker to persist throughout differentiation (Chang, 1994).
Specificity
Antibody recognizes Human CD7 antigen.
Immunogen
CEM T-cell line (ATTC CCL-199), a T-lymphoblastold cell line.
Application
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
This Milli-Mark Anti-CD7-PE Antibody, clone CBC.37 is validated for use in FC for the detection of CD7.
Quality
Evaluated by flow cytometry using human PBMCs
Target description
40 kDa (Bowen, 2002 and 1997)
Physical form
Protein A purified
Purified Mouse monoclonal IgG2b conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Storage and Stability
Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
Analysis Note
Control
PBMCs
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
- UPC:
- 41116126
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- FCMAB175P