CAYMAN CHEMICAL
MK-0752-5 mg
A potent, reversible inhibitor of &gamma-secretase, reducing the cleavage of APP to A&beta40 in SH-SY5Y cells with an IC50 value of 5 nM orally bioavailable and crosses the blood-brain barrier, as orally administered MK-0752
A potent, reversible inhibitor of γ-secretase, reducing the cleavage of APP to Aβ40 in SH-SY5Y cells with an IC50 value of 5 nM; orally bioavailable and crosses the blood-brain barrier, as orally administered MK-0752 dose-dependently reduces the generation of new amyloid β protein in the brain of rhesus monkeys.
Specifications
- UPC:
- 51152003
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- Quantity:
- 1
- Unit of Measurement:
- EA
- WeightUOM:
- LB
- MPN:
- 16706-5



