ML192 (C008B-269183)

ML192 is a selective ligand antagonist of GPR55 . ML192 inhibits the β-arrestin trafficking, ERK1/2 phosphorylation and PKCβII translocationIn Vitro（for reference only）ML192 inhibits the β-arrestin trafficking induced by 10 μM L-α lysophosphatidylinositol (LPI) or 1 μM ML186 with IC 50 values of 0.70 µM and 0.29 µM, respectively. ML192 significantly inhibits ERK1/2 phosphorylation in GPRSS-expressing U2OS cells with an IC 50 value of 1.1 µM. ML192 (0, 10, 30 and 100 µM) reduces the translocation of PKCβII in cells with the Wild-Type GPR55 receptor. Form:SolidIC50& Target:ERK2 ERK1 PKCβII

Specifications & Purity: ML192 is a selective ligand antagonist of GPR55 . ML192 inhibits the β-arrestin trafficking, ERK1/2 phosphorylation and PKCβII translocationIn Vitro（for reference only）ML192 inhibits the β-arrestin trafficking induced by 10 μM L-α lysophosphatidylinositol (LPI) or 1 μM ML186 with IC 50 values of 0.70 µM and 0.29 µM, respectively. ML192 significantly inhibits ERK1/2 phosphorylation in GPRSS-expressing U2OS cells with an IC 50 value of 1.1 µM. ML192 (0, 10, 30 and 100 µM) reduces the translocation of PKCβII in cells with the Wild-Type GPR55 receptor. Form:SolidIC50& Target:ERK2 ERK1 PKCβII

Grade: Moligand™

Molecular Formula: C20H22N4O2S

Molecular Weight: 382.48

PubChem CID: 1434953

Isomeric SMILES: CC1=NC(=C2C3=C(CCCC3)SC2=N1)N4CCN(CC4)C(=O)C5=CC=CO5

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

51441703

Weight:

1.09 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

M648928-100mg

Country of Origin:

China

CAS:

460331-61-7

Product Size:

100mg

Harmonized Tariff Code:

2931.90.90