ML380 (C008B-267352)

ML380 is a potent, subtype-selective, and brain-penetrant positive allosteric modulator (PAM) of M5 mAChR, with EC50s of 190 and 610 nM for human and rat M5, respectively. ML380 exhibits moderate selectivity versus the M1 and M3 mAChR subtypes. ML380 could increase the affinity of ACh for the M5 mAChR.

Specifications & Purity: ML380 is a potent, subtype-selective, and brain-penetrant positive allosteric modulator (PAM) of M5 mAChR, with EC50s of 190 and 610 nM for human and rat M5, respectively. ML380 exhibits moderate selectivity versus the M1 and M3 mAChR subtypes. ML380 could increase the affinity of ACh for the M5 mAChR.

Grade: Moligand™

Molecular Formula: C23H25F3N4O3S

Molecular Weight: 494.53

PubChem CID: 71737672

Isomeric SMILES: CCN(CC1=CC=CC=C1C(F)(F)F)C(=O)C2CCN(CC2)S(=O)(=O)C3=CC4=C(C=C3)NN=C4

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

51292804

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

M647140-1mg

Country of Origin:

China

CAS:

1627138-52-6

Product Size:

1mg

Harmonized Tariff Code:

2931.90.90