MMP-3 INHIBITOR I 1PC X 5MG (C005B-228070)

General description

Inhibits matrix metalloproteinase-3 (stromelysin) (IC₅₀ = 5 µM). The inhibitor is based on a segment from the conserved region of the NH₂-terminal propeptide domain.

Inhibits the matrix metalloproteinase MMP-3 (IC₅₀ = 5 µM).

Biochem/physiol Actions

Cell permeable: no

Primary Target
MMP-3

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 5 µM against MMP-3

Warning

Toxicity: Standard Handling (A)

Sequence

Ac-Arg-Cys-Gly-Val-Pro-Asp-NH₂

Physical form

Supplied as a trifluroacetate salt.

Reconstitution

Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.

Other Notes

Fotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
Hanglow, A.C., et al. 1993. Agents Actions 39, C148.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Molecular Weight: 686.78. Empirical Formula: C₂₇H₄₆N₁₀O₉S. Quality Level: 100. Assay: ≥. 90% (HPLC). form: solid. manufacturer/tradename: Calbiochem^®. . storage condition: OK to freeze, desiccated (hygroscopic). color: white. solubility: water: 1 . mg/mL. shipped in: ambient. storage temp.: −. 20°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.

UPC:

51111754

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

5

Unit of Measurement:

MG

MPN:

444218-5MG

Controlled Substances and Cyanide:

Yes