Mocravimod hydrochloride (C007B-374885)

Mocravimod hydrochloride (KRP-203), an immunosuppressant, is a potent and orally active S1PR1 (sphingosine 1-phosphate receptor type 1) agonistIn VivoMocravimod hydrochloride (KRP-203) ameliorates atherosclerosis in LDL-R ?/? Mice . ?/nMocravimod hydrochloride (KRP-203) (orally; 0.1 and 1 mg/kg/day; for 100 days) prolongs graft survival and attenuates chronic rejection in mHC-disparate rat heart allografts. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Inbred male DA (MHC haplotype: RT1 a ) ratsDosage: 0.1 and 1 mg/kg Administration: Orally; daily; for 100 days Result: Prolonged graft survival and attenuated chronic rejection in mHC-disparate rat heart allografts.Form:SolidIC50& Target:S1PR1. Specification: 0.99 Molecular Formula: C24H27Cl2NO3S Molecular Weight: 480.46 PubChem CID: 11155873 Isomeric SMILES: C1=CC=C(C=C1)COC2=CC(=CC=C2)SC3=CC(=C(C=C3)CCC(CO)(CO)N)Cl.Cl

UPC:

51262007

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

WeightUOM:

LB

MPN:

M649815-10mg

CAS:

509088-69-1

Product Size:

10mg