CAYMAN CHEMICAL
MS-PPOH-1 mg
Arachidonic acid is converted by microsomal CYP450 enzymes to a variety of epoxides, &omega-1 and &omega-hydroxylated compounds via what is known as the epoxidase pathway. MS-PPOH is a selective inhibitor of the epoxygenation reactions catalyzed
Arachidonic acid is converted by microsomal CYP450 enzymes to a variety of epoxides, ω-1 and ω-hydroxylated compounds via what is known as the epoxidase pathway. MS-PPOH is a selective inhibitor of the epoxygenation reactions catalyzed by specific CYP450 isozymes. MS-PPOH inhibits the formation of arachidonate 11,12-epoxides by CYP4A2 and CYP4A3 enzymes with an IC50 value of 13 µM, but has no effect on the formation of 20-HETE, the ω-hydroxylation product of CYP4A1.
Specifications
- UPC:
- 51173008
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- Quantity:
- 1
- Unit of Measurement:
- EA
- WeightUOM:
- LB
- MPN:
- 75770-1



