MSN-50 (C007B-374451)

MSN-50 is a Bax and Bak oligomerization inhibitor. MSN-50 efficiently inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotectionIn VitroMSN-50 (0~10 uM) inhibits dye release from liposomes in a concentration-dependent fashion. MSN-50 (0~40 uM) inhibits tBid/Bax-mediated MOMP (mitochondrial outer membrane permeabilization) in a concentration-dependent manner and shows concentration-dependent inhibition of Bak-mediated MOMP. MSN-50 inhibits both Bax and Bak after activation by either cBid or Bim. MSN-50 (5 μM; BMK cells) inhibits apoptosis induced by actinomycin D and staurosporin (STS) . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:Bax Bak. Specification: 0.98 Molecular Formula: C36H38BrN3O6 Molecular Weight: 688.619 PubChem CID: 154730935

UPC:

51111733

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

M647974-50mg

CAS:

1592908-75-2

Product Size:

50mg