Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic . Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC 50 and MIC 90 values both of 0.12 mg/L. Murepavadin also can target theAppearance:SolidIC50& Target:MIC50: 0.12 mg/L( P. aeruginosa ) MIC90: 0.12 mg/L( P. aeruginosa ) IC50: 5.84 μM (gentamicin)In Vitro:Murepavadin has activity against P. aeruginosa with MIC 50 and MIC 90 values both of 0.12 mg/L. Murepavadin inhibits megalin-mediated uptake of gentamicin in vitro with an IC 50 value of 5.84 μM. MCE has not independently confirmed the accuraIn Vivo:Murepavadin (s.c.; 0-10mg/kg) is active in pre-clinical animal models including infections with XDR isolates. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Murine models of P. aeruginosBiological Activity:Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic . Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC 50 and MIC 90 values both of 0.12 mg/L. Murepavadin also can target the
Specification: ≥99%
Molecular Formula: C73H112N22O16(free base)
Molecular Weight: 1553.837(free base)
- UPC:
- 51281650
- Condition:
- New
- Availability:
- 5-10 days
- Weight:
- 0.07 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- M659012-1mg
- CAS:
- 944252-63-5
- Product Size:
- 1mg
