Murepavadin TFA

Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic . Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC 50 and MIC 90 values both of 0.12 mg/L. Murepavadin also can target theAppearance:SolidIC50& Target:MIC50: 0.12 mg/L( P. aeruginosa ) MIC90: 0.12 mg/L( P. aeruginosa ) IC50: 5.84 μM (gentamicin)In Vitro:Murepavadin has activity against P. aeruginosa with MIC 50 and MIC 90 values both of 0.12 mg/L. Murepavadin inhibits megalin-mediated uptake of gentamicin in vitro with an IC 50 value of 5.84 μM. MCE has not independently confirmed the accuraIn Vivo:Murepavadin (s.c.; 0-10mg/kg) is active in pre-clinical animal models including infections with XDR isolates. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Murine models of P. aeruginosBiological Activity:Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic . Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC 50 and MIC 90 values both of 0.12 mg/L. Murepavadin also can target the

Specification: ≥99%

Molecular Formula: C73H112N22O16(free base)

Molecular Weight: 1553.837(free base)

UPC:

51281650

Condition:

New

Weight:

0.07 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

M659012-1mg

CAS:

944252-63-5

Product Size:

1mg