N-(3-pyridyl)-Indomethacin amide-50 mg

N-3PyIA is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2. N-3PyIA selectively inhibits human recombinant COX-2 with an IC₅₀ of 52 nM. It is about 1,300 times less potent as an inhibitor of ovine COX-1. However, N-3PyIA does not distinguish between ovine COX-1 and -2. The IC₅₀ values for ovine COX-1 and -2 are 75 and 50 µM, respectively.

UPC:

51112600

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

WeightUOM:

LB

MPN:

70274-50

Controlled Substances and Cyanide:

Yes