N-Benzyl-p-Toluenesulfonamide (C007B-238373)

product description：An aryl sulphonamide that acts as a potent inhibitor of Ca2+-stimulated myosin S1 actin-stimulated ATPase activity (IC50 = ~5 µM). Also blocks actin-stimulated ATPase activity with similar potency (IC50 = 5 µM). Reversibly blocks gliding motility of skeletal muscle myosin (IC50<2 µM). Less effective in suppressing contraction in rat myocardial and rabbit slow twitch muscle compared to skeletal muscle. Does not inhibit platelet myosin II.A potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 = ~ 5 µM) and reversibly blocks the gliding motility. It also weakens myosin’s interaction with F-actin. Much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II. Specification: ≥98.0%(HPLC) MDL Number: MFCD00159328 Molecular Formula: C14H15NO2S Molecular Weight: 261.34 PubChem CID: 95801 Isomeric SMILES: CC1=CC=C(C=C1)S(=O)(=O)NCC2=CC=CC=C2 Beilstein Registry Number: 12(3)2328 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/N131765-SCI_31af44136cdd9aed22af69f02b6c2e16.pdf

UPC:

51262302

Condition:

New

Weight:

3.02 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

N131765-5g

CAS:

1576-37-0

Health Hazards:

Toxic

Product Size:

5g

Hazard Statement Codes:

H301

Precautionary Statement Codes:

P264:P270:P330:P405:P501