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Sigma-Aldrich

N-FLUOROBENZENESULFONIMIDE 97%

N -Fluorobenzenesulfonimide (NFSi) is a commonly used electrophilic fluorinating agent in organic synthesis to introduce fluorine into neutral organic molecules. It is also used to fluorinate nucleophilic substrates such as reactive organometallic

Description

General description

N-Fluorobenzenesulfonimide (NFSi) is a commonly used electrophilic fluorinating agent in organic synthesis to introduce fluorine into neutral organic molecules. It is also used to fluorinate nucleophilic substrates such as reactive organometallic species and malonate anions.
NFSi can be synthesized by the reaction of benzenesulfonimide with fluorine.

Application

Reagent employed in a palladium-catalyzed enantioselective fluorination of t-butoxycarbonyl lactones and lactams. Also used in the electrophilic difluorination of dihalopyridines with butyl lithium and in the direct conversion of alcohols to dibenzenesulfonamides with triphenylphosphine.

Stable, easy-to-handle, crystalline material which readily transfers F+ to enolates and carbanions.

Specifications
UPC:
51472700
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
5
Unit of Measurement:
GR
MPN:
392715-5G
CAS:
133745-75-2
Catalog No. C005B-015431
Price: $203.61
List Price: $226.23
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