N-(p-Amylcinnamoyl)anthranilic acid (C007B-605347)

N-(p-Amylcinnamoyl) anthranilic Acid (ACA), a cell permeable inhibitor of PLA2, has been reported to inhibit α-ketoisocaproic acid and glyceraldehyde-induced insulin secretion, as well as glucose-induced insulin secretion. Additionally, by inhibiting PLA2, ACA consequentially suppresses glucose-induced arachidonic acid formation in cells. Furthermore, research has shown ACA to modulate the activity of different transient receptor potential channels. In particular, ACA's blocking ability of diacylglycerol-activated TRP channels is of special interest since it offers the opportunity to interfere with receptor-induced Ca2+-dependent signaling processes in vascular smooth muscle cells and platelets.

PLA 2 inhibitor

Specifications & Purity: Moligand™, ≥96%

Grade: Moligand™

Molecular Formula: C21H23NO3

Molecular Weight: 337.4

PubChem CID: 5353376

Isomeric SMILES: CCCCCC1=CC=C(C=C1)/C=C/C(=O)NC2=CC=CC=C2C(=O)O

More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/A275778-SCI_07955b7b02b43f6bc86477e5b9bc7406.pdf

UPC:

51172501

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

A275778-500mg

CAS:

110683-10-8

Product Size:

500mg

Hazard Statement Codes:

H400;H410

Precautionary Statement Codes:

P273;P391;P501