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Sigma-Aldrich

NAPROXEN SODIUM (C005B-454860)

General description Naproxen belongs to phenylacetic acid class of Non-steroidal anti-inflammatory drugs (NSAIDs). Application Naproxen sodium has been used to evaluate the thermodynamics of biomolecular interaction with bovine and human serum

Description

General description

Naproxen belongs to phenylacetic acid class of Non-steroidal anti-inflammatory drugs (NSAIDs).

Application

Naproxen sodium has been used to evaluate the thermodynamics of biomolecular interaction with bovine and human serum albumin. It has also been used to evaluate its efficiency in reducing the response of spinal dorsal horn neurons to noxious knee joint rotation.

Biochem/physiol Actions

Naproxen binds preferably to serum albumin. The S-enantiomer of naproxen is 28-fold more potential as an anti-inflammatory drug compared to the R-isomer. The R-isomer is found to be a liver toxin and causes gastrointestinal disorders.

Cyclooxygenase (Prostaglandin H synthase 1 and 2) inhibitor.

Features and Benefits

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Specifications
UPC:
51262603
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
25
Unit of Measurement:
GM
MPN:
M1275-25G
CAS:
26159-34-2
Controlled Substances and Cyanide:
Yes
Catalog No. C005B-454860
Price: $590.59
List Price: $656.21
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