Necrostatin 2 S enantiomer (C007B-378992)

Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin 2. Necrostatin 2 is a potent necroptosis inhibitor , acts as a RIPK1 inhibitor lacking the IDO-targeting effect.Target: RIPK1 Necrostatin 2 is a potent in vitro necroptosis inhibitors (exemplified by 1, EC50-0.05 uM) that also were efficacious in an animal model of ischemic stroke. Many Necroptosis inhibitor derivatives are designed for researchers. Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. It can be induced in a FADD-deficient variant of human Jurkat T cells treated with TNF-a. 5-(1H-Indol-3-ylmethyl)-2-thiohydantoins and 5-(1H-indol-3-ylmethyl)hydantoins were found to be potent necroptosis inhibitors (called necrostatins).Form:Solid. Specification: 0.99 Molecular Formula: C13H12ClN3O2 Molecular Weight: 277.71 PubChem CID: 44404825 Isomeric SMILES: CN1C(=O)[C@@H](NC1=O)CC2=CNC3=C2C=CC=C3Cl

UPC:

51471808

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

N650407-50mg

CAS:

852391-20-9

Product Size:

50mg