Nedisertib (M3814)

Nedisertib acts as a modulator of ABCG2, capable of reversing ABCG2-mediated multidrug resistance (MDR), thus providing new strategies for combination therapy. By inhibiting DNA double-strand break repair, Nedisertib can enhance the efficacy of chemotherapy and radiotherapy. Nedisertib exhibits antitumor activity.

DNA-PK Inhibitors

Specifications & Purity: Nedisertib acts as a modulator of ABCG2, capable of reversing ABCG2-mediated multidrug resistance (MDR), thus providing new strategies for combination therapy. By inhibiting DNA double-strand break repair, Nedisertib can enhance the efficacy of chemotherapy and radiotherapy. Nedisertib exhibits antitumor activity.

Grade: Moligand™

Molecular Formula: C24H21ClFN5O3

Molecular Weight: 481.91

PubChem CID: 86292849

Isomeric SMILES: COC1=NN=C(C=C1)[C@H](C2=C(C=C(C(=C2)C3=NC=NC4=C3C=CC(=C4)N5CCOCC5)F)Cl)O

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

41141910

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

N414073-1mg

Country of Origin:

China

CAS:

1637542-33-6

Product Size:

1mg

Harmonized Tariff Code:

2931.90.90