NMI 8739 (C007B-379112)

NMI 8739 is a dopamine D 2 autoreceptor agonist, which is an amine conjugate of the DHA carrier and the neurotransmitter dopamine.In VitroNMI 8739 is a dopamine D 2 autoreceptor agonist, which is an amine conjugate of the DHA carrier and the neurotransmitter dopamine. NMI 8739 reduces nitric oxide (NO) production in LPS-stimulated RAW264.7 Macrophages. NMI 8739 elicits concentration-dependent suppression of CCL-20, MCP-1 and IL-6 Release in RAW264.7 macrophages after LPS-stimulation. Production of PGE2 is concentration-dependently suppressed with a reduction of 25.3% at 100 nM NMI 8739 and a 75% reduction for 1 μM NMI 8739. 2 μM NMI 8739 significantly inhibits IL-6 and CCL-20 release up to 49% and 37%, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Oil. Specification: 0.99 Molecular Formula: C30H41NO3 Molecular Weight: 463.65 PubChem CID: 6443994 Isomeric SMILES: CC/C=C/C/C=C/C/C=C/C/C=C/C/C=C/C/C=C/CCC(=O)NCCC1=CC(=C(C=C1)O)O

UPC:

51143008

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

N651636-10mg

CAS:

129024-87-9

Product Size:

10mg