Sigma-Aldrich
NOURSEOTHRICIN SULFATE SUITABLE FOR CELL CULTURE (C005B-444924)
General description Chemical structure: peptidyl nucleoside, aminoglycoside antibiotic. Nourseothricin (NTC) is a mixture of the related compounds streptothricin C, D, E, and F.
General description
Chemical structure: peptidyl nucleoside, aminoglycoside antibiotic. Nourseothricin (NTC) is a mixture of the related compounds streptothricin C, D, E, and F.
Application
Nourseothricin is used as a dominant selection antibiotic for genetically modified bacteria, yeasts, fungi, protozoa and plants.
Biochem/physiol Actions
Nourseothricin inhibits biosynthesis and induces miscoding. Resistance to nourseothricin is mediated by the sat1 encoded N-acetyltransferase. Nourseothricin is inactivated by acetylation of the β-amino group of the β-lysin.
Antifungal effective against Candida albicans. Candida species transformed with the gene encoding nourseothricin acetyltransferase (CaNAT1) were resistant to nourseothricin.
Packaging
10mg, 50mg
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
- UPC:
- 51302330
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- Quantity:
- 50
- Unit of Measurement:
- MG
- MPN:
- N0186-50MG
- Controlled Substances and Cyanide:
- Yes



