Nutlin-3

Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM; stabilizes p73 in p53-deficient cells.Disrupts MDM2-p53 interaction, inducing apoptosis.

Potent, selective MDM2 antagonist

Specifications & Purity: Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM; stabilizes p73 in p53-deficient cells.Disrupts MDM2-p53 interaction, inducing apoptosis.

MDL Number: MFCD07784509

Molecular Formula: C30H30Cl2N4O4

Molecular Weight: 581.49

EC Number: 637-233-8

PubChem CID: 216345

Isomeric SMILES: CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/N126055-SCI_722ef414ee45334195afad9bcf547f52.pdf

UPC:

51173231

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

N126055-5mg

Country of Origin:

China

CAS:

548472-68-0

Product Size:

5mg

Harmonized Tariff Code:

2931.90.90

Hazard Statement Codes:

H315;H319;H335

Precautionary Statement Codes:

P261;P264;P271;P280;P321;P302+P352;P304+P340;P305+P351+P338;P362+P364;P405;P403+P233;P501;P264+P265;P337+P317;P332+P317;P319