CAYMAN CHEMICAL
NVP-BKM120-5 mg
An orally bioavailable inhibitor of class I PI3K isoforms, potently blocking, in vitro, both p110&alpha (IC50 = 52 nM) and p110&beta (IC50 = 166 nM) much less effectively inhibits the class III PI3K Vps34 and mTOR and has no effect on PI4K&beta
Description
An orally bioavailable inhibitor of class I PI3K isoforms, potently blocking, in vitro, both p110α (IC50 = 52 nM) and p110β (IC50 = 166 nM); much less effectively inhibits the class III PI3K Vps34 and mTOR and has no effect on PI4Kβ and several other kinases; inhibits tumor growth in vivo.
Specifications
- UPC:
- 51111862
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- Quantity:
- 1
- Unit of Measurement:
- EA
- WeightUOM:
- LB
- MPN:
- 11587-5
- CAS:
- 944396-07-0
Catalog No.
C003B-360420
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