OLIGOMYCIN FROM STREPTOMYCES DIASTATOCHROMOGENES >=90% TOTAL OLIGOMYCINS BASIS (HPLC) (C005B-442298)

Catalog No.: C005B-442298
Mfr. No.: O4876-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $239.37

List Price: $265.97

General description Chemical structure: macrolide Application Oligomycin from Streptomyces diastatochromogenes is used: in the inhibition of mitochondrial ATP production Leigh syndrome (LS) cells. in ATP-linked respiration and maximal

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Description
Specifications

General description

Chemical structure: macrolide

Application

Oligomycin from Streptomyces diastatochromogenes is used:

in the inhibition of mitochondrial ATP production Leigh syndrome (LS) cells.
in ATP-linked respiration and maximal capacity respiration assay in astrocytes.
in measurement of oxygen consumption rate (OCR) and extracellular acidification rates in breast cancer cell lines.

Biochem/physiol Actions

Oligomycin belongs to the macrolide group of antibiotics. It inhibits mitochondrial ATP-synthase enzyme and phosphoryl group transfer. Oligomycin interacts with ATP synthase subunit-c in the Fo portion and impairs proton transport.

Other Notes

A mixture of oligomycins A, B, and C.

UPC:: 51102800
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: O4876-5MG
CAS:: 1404-19-9

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