Org41841 (C008B-267288)

Functional assays demonstrate that Org41841 is a partial agonist of both luteinizing hormone/chorionic gonadotropin receptor (LHCGR) and thyroid-stimulating hormone receptor (TSHR) with EC 50 s of 0.2 and 7.7 μM, respectively. Treatment of L570F with Org41841 reveals an improved EC 50 of 800 nM. M9 responds to Org41841 with an improved EC 50 of 2700 nM and a greatly improved efficacy for signaling to 99% of the maximal value observed for thyroid-stimulating hormone (TSH) stimulation of thyroid-stimulating hormone receptor (TSHR).

Specifications & Purity: Functional assays demonstrate that Org41841 is a partial agonist of both luteinizing hormone/chorionic gonadotropin receptor (LHCGR) and thyroid-stimulating hormone receptor (TSHR) with EC 50 s of 0.2 and 7.7 μM, respectively. Treatment of L570F with Org41841 reveals an improved EC 50 of 800 nM. M9 responds to Org41841 with an improved EC 50 of 2700 nM and a greatly improved efficacy for signaling to 99% of the maximal value observed for thyroid-stimulating hormone (TSH) stimulation of thyroid-stimulating hormone receptor (TSHR).

Grade: Moligand™

Molecular Formula: C19H22N4O2S2

Molecular Weight: 402.53

PubChem CID: 9887381

Isomeric SMILES: CC(C)(C)NC(=O)C1=C(C2=C(N=C(N=C2S1)SC)C3=CC(=CC=C3)OC)N

Storage Temperature: Protected from light;Store at -20°C;Argon charged

Shipped in: Ice chest + Ice pads

UPC:

51132203

Weight:

1.09 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

O648726-100mg

Country of Origin:

China

CAS:

301847-37-0

Product Size:

100mg

Harmonized Tariff Code:

2931.90.90