PANOBINOSTAT (C005B-309624)

Biochem/physiol Actions

Panobinostat (LBH589) is an orally active, potent, cinnamoyl hydroxamate-type pan-histone deacetylase inhibitor (class I HDAC1/2/3/8 IC50 = 2.5/13.2/2.1/277 nM; IIA HDAC4/5/7/9 IC50 = 203/7.8/531/5.7 nM; IIB HDAC6/10 IC50 = 10.5/2.3 nM, IV HDAC11 IC50 = 2.7 nM) with anti-cancer efficacy in vitro and in vivo.

UPC:

51111758

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

50

Unit of Measurement:

MG

MPN:

SML3060-50MG

CAS:

404950-80-7