Calbiochem
PAROXETINE HYDROCHLORIDE (C005B-007838)
A very potent uptake inhibitor highly selective for 5-HT transporter (K i = 0.065 nM and 0.
Description
General description
A very potent uptake inhibitor highly selective for 5-HT transporter (Ki = 0.065 nM and 0.05 nM for human and rat 5-HT transporters, respectively). A popular antidepressant drug of the SSRI type. Used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms.
Biochem/physiol Actions
Primary Target
5-HT Uptake Transporter
Warning
Toxicity: Standard Handling (A)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Brittain, G., et al. 2012. Profiles of drug substances, excipients, and related methodology.38, 407.
Bourin, M., et al. 2001. CNS Drug Rev.7, 25.
Thomas, R., et al. 1997. Psychopharmacology (Berl).93, 193.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Specifications
- UPC:
- 51294513
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- Quantity:
- 10
- Unit of Measurement:
- MG
- MPN:
- 5061250001
- CAS:
- 110429-35-1
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