PD 180970

PD180970 is a highly potent and ATP-competitive p210Bcr-Abl kinase inhibitor, with an IC50 of 5 nM for inhibiting the autophosphorylation of p210Bcr-Abl. PD180970 also inhibits Src and KIT kinase with IC50s of 0.8 nM and 50 nM, respectively. PD180970 indcues apoptosis of K562 leukemic cells, and can be used for chronic myelogenous leukemia research.

p210Bcr/Ablkinase inhibitor; also inhibits c-Src and KIT

Specifications & Purity: PD180970 is a highly potent and ATP-competitive p210Bcr-Abl kinase inhibitor, with an IC50 of 5 nM for inhibiting the autophosphorylation of p210Bcr-Abl. PD180970 also inhibits Src and KIT kinase with IC50s of 0.8 nM and 50 nM, respectively. PD180970 indcues apoptosis of K562 leukemic cells, and can be used for chronic myelogenous leukemia research.

Molecular Formula: C21H15Cl2FN4O

Molecular Weight: 429.27

EC Number: 683-687-5

PubChem CID: 5311104

Isomeric SMILES: CC1=C(C=CC(=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl)F

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/P287860-SCI_8717acbd0709a3c3e8db04eed25cfc97.pdf

UPC:

51373462

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

P287860-1mg

Country of Origin:

China

CAS:

287204-45-9

Product Size:

1mg

Harmonized Tariff Code:

2931.90.90

Health Hazards:

Toxic

Hazard Statement Codes:

H301;H413

Precautionary Statement Codes:

P264;P270;P273;P321;P330;P405;P501;P301+P316