PDK1-IN-RS2 (C007B-385385)

PDK1-IN-RS2 is a mimic of peptide docking motif (PIFtide) and is a substrate-selective PDK1 inhibitor with a K d of 9 μM. PDK1-IN-RS2 suppresses the activation of the downstream kinases S6K1 by PDK1In VitroPDK1-IN-RS2 stimulates the catalytic activity of PDK1 toward a peptide substrate by sixfold. The sulfonyl group of PDK1-IN-RS2 interacts with Arg131 through a salt bridge, because the sulfonamide is likely ionized under the crystallization conditions. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:Kd: 9 μM (PDK1). Specification: 0.98 Molecular Formula: C15H9ClN2O2S3 Molecular Weight: 380.89

UPC:

51162627

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

P646789-25mg

CAS:

1643958-89-7

Product Size:

25mg