Pentafluorophenol

General description

Pentafluorophenol is widely used as a precursor in both solution and solid-phase peptide synthesis. It is also involved in the preparation of aromatic fluoro derivatives.

Application

Pentafluorophenol can be used as a reactant to synthesize pentafluorophenyl esters from:

• N-protected amino acid in the presence of dicyclohexylcarbodiimide and ethyl acetate.
• t-Butoxycarbonyl-L-alanylglycinein the presence of 1-ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride.
• Aliphatic dicarboxylic acids in the presence of pyridine, diisopropylcarbodiimide, and acetonitrile.

It can also be used as a reactant to synthesize pentafluorophenyl formate which can be used as a formylating agent in organic synthesis.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

UPC:

51332878

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

5

Unit of Measurement:

G

WeightUOM:

LB

MPN:

103799

CAS Number:

771-61-9