PF-00835231

PF-00835231 PF-00835231 is a 3CL pro (M pro ) inhibitor that may targets SARS-CoV-2 protease 3CL pro as a potential new treatment for COVID-19.Targets3CLproIn vitroA time-of-drug-addition approach delineates the timing of early SARS-CoV-2 life cycle steps in A549+ACE2 cells and validates PF-00835231\'s early time of action. In a model of the human polarized airway epithelium, PF-00835231 potently inhibits SARS-CoV-2 at low micromolar concentrations. PF-00835231 exhibits the potential as an effective SARS-CoV-2 antiviral.Cell Research(from reference)Cell lines：A549 cells, human airway epithelial cultures (HAEC) Concentrations：1 nM-10 μM Incubation Time：0-4 h

SARS-CoV Inhibitors

Specifications & Purity: PF-00835231 PF-00835231 is a 3CL pro (M pro ) inhibitor that may targets SARS-CoV-2 protease 3CL pro as a potential new treatment for COVID-19.Targets3CLproIn vitroA time-of-drug-addition approach delineates the timing of early SARS-CoV-2 life cycle steps in A549+ACE2 cells and validates PF-00835231\'s early time of action. In a model of the human polarized airway epithelium, PF-00835231 potently inhibits SARS-CoV-2 at low micromolar concentrations. PF-00835231 exhibits the potential as an effective SARS-CoV-2 antiviral.Cell Research(from reference)Cell lines：A549 cells, human airway epithelial cultures (HAEC) Concentrations：1 nM-10 μM Incubation Time：0-4 h

Grade: Moligand™

Molecular Formula: C24H32N4O6

Molecular Weight: 472.53

PubChem CID: 11561899

Isomeric SMILES: CC(C)C[C@@H](C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO)NC(=O)C2=CC3=C(N2)C=CC=C3OC

Storage Temperature: Protected from light;Store at -20°C

Shipped in: Ice chest + Ice pads

More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/P414478-SCI_4a13b93fae185df41078848809e99d9c.pdf

UPC:

51373408

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

P414478-1mg

Country of Origin:

China

CAS:

870153-29-0

Product Size:

1mg

Harmonized Tariff Code:

2931.90.90