PF-4840154 (C008B-270744)

PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel with EC 50 s of 97 and 23 nM, respectively. PF-4840154 elicits TrpA1-mediated nocifensive behaviour in mouseIn VivoPF-4840154 (30 nmol; intraplantar) elicits TrpA1-mediated nocifensive behaviour in mouse . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Female CD1 mice (25-30g) (In TrpA1+/+ mice) Dosage: 30 nmol Administration: Intraplantar (i.pl) injection Result: Elicited robust licking behavior.Form:SolidIC50& Target:IC50: 97 nM (rTrpA1), 23 nM (hTrpA1)

Specifications & Purity: PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel with EC 50 s of 97 and 23 nM, respectively. PF-4840154 elicits TrpA1-mediated nocifensive behaviour in mouseIn VivoPF-4840154 (30 nmol; intraplantar) elicits TrpA1-mediated nocifensive behaviour in mouse . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Female CD1 mice (25-30g) (In TrpA1+/+ mice) Dosage: 30 nmol Administration: Intraplantar (i.pl) injection Result: Elicited robust licking behavior.Form:SolidIC50& Target:IC50: 97 nM (rTrpA1), 23 nM (hTrpA1)

Grade: Moligand™

Molecular Formula: C26H38N6O2

Molecular Weight: 466.62

PubChem CID: 53380803

Isomeric SMILES: CC(C)CNC1=NC(=NC=C1C(=O)NCC2=CC=CC=C2)N3CCN(CC3)CC4CCCOC4

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

51283913

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

P650704-25mg

Country of Origin:

China

CAS:

1332708-14-1

Product Size:

25mg

Harmonized Tariff Code:

2931.90.90