PF-4840154 (C007B-386828)

PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel with EC 50 s of 97 and 23 nM, respectively. PF-4840154 elicits TrpA1-mediated nocifensive behaviour in mouseIn VivoPF-4840154 (30 nmol; intraplantar) elicits TrpA1-mediated nocifensive behaviour in mouse . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Female CD1 mice (25-30g) (In TrpA1+/+ mice) Dosage: 30 nmol Administration: Intraplantar (i.pl) injection Result: Elicited robust licking behavior.IC50& Target:IC50: 97 nM (rTrpA1), 23 nM (hTrpA1). Specification: 10mM in DMSO Molecular Formula: C26H38N6O2 Molecular Weight: 466.62

UPC:

51183709

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

P656380-1ml

CAS:

1332708-14-1

Product Size:

1ml