PF 6274484 (C007B-410134)

PF 6274484 is a high affinity, irreversible covalent inhibitor of EGFR kinase with Ki of 0.14 nM. PF 6274484 inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R/T790M in H1975 cells with IC50 of 5.8 nM and 6.6 nM, respectively. Specification: ≥98%(HPLC) Molecular Formula: C18H14ClFN4O2 Molecular Weight: 372.78 PubChem CID: 74766099 Isomeric SMILES: COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)NC(=O)C=C Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/P288199-SCI_a5b349249c54fec820a4abae61de68df.pdf

UPC:

51241904

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

P288199-10mg

CAS:

1035638-91-5

Product Size:

10mg