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PINACIDIL MONOHYDRATE (C005B-440378)

Catalog No.
C005B-440378
Mfr. No.
P154-500MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
500
UOM
MG
Price: $1,160.08
List Price: $1,288.98

Application Pinacidil monohydrate has been used: in repolarization studies by infusing into left anterior descending artery (LAD) to induce ATP-sensitive K + (K ATP ) current in ventricular myocytes for electrophysiological studies as a

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Application

Pinacidil monohydrate has been used:

  • in repolarization studies by infusing into left anterior descending artery (LAD)
  • to induce ATP-sensitive K+ (KATP) current in ventricular myocytes for electrophysiological studies
  • as a KATP opener to treat myocardial cells

Biochem/physiol Actions

K+ channel activator; antihypertensive.

Pinacidil is a KATP channel agonist. It protects cardiomyocytes by preventing loss of mitochondrial membrane potential. It prevents the caspase 3 activation in hypoxia/reoxygenation injury.

UPC:
51432108
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
P154-500MG
CAS:
85371-64-8

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