Sigma-Aldrich
PINACIDIL MONOHYDRATE (C005B-440378)
Application Pinacidil monohydrate has been used: in repolarization studies by infusing into left anterior descending artery (LAD) to induce ATP-sensitive K + (K ATP ) current in ventricular myocytes for electrophysiological studies as a
Description
Application
Pinacidil monohydrate has been used:
- in repolarization studies by infusing into left anterior descending artery (LAD)
- to induce ATP-sensitive K+ (KATP) current in ventricular myocytes for electrophysiological studies
- as a KATP opener to treat myocardial cells
Biochem/physiol Actions
K+ channel activator; antihypertensive.
Pinacidil is a KATP channel agonist. It protects cardiomyocytes by preventing loss of mitochondrial membrane potential. It prevents the caspase 3 activation in hypoxia/reoxygenation injury.
Specifications
- UPC:
- 51432108
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- Quantity:
- 500
- Unit of Measurement:
- MG
- MPN:
- P154-500MG
- CAS:
- 85371-64-8
Catalog No.
C005B-440378
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