PK68

PK68 is a specifical type II inhibitor of receptor-interacting kinase 1 (RIPK1) with an IC50 of ~90 nM, displays inhibition of RIPK1-dependent necroptosis. PK68 powerfully ameliorates TNF-induced systemic inflammatory response syndrome, and can be used for the research of inflammatory disorders and cancer metastasis.

Specifications & Purity: PK68 is a specifical type II inhibitor of receptor-interacting kinase 1 (RIPK1) with an IC50 of ~90 nM, displays inhibition of RIPK1-dependent necroptosis. PK68 powerfully ameliorates TNF-induced systemic inflammatory response syndrome, and can be used for the research of inflammatory disorders and cancer metastasis.

Grade: Moligand™

Molecular Formula: C22H24N4O3S

Molecular Weight: 424.52

PubChem CID: 134203923

Isomeric SMILES: CC1=C(C=C(C=N1)C2=CC3=C(C=C2)N=C(S3)NC(=O)C)NC(=O)OC4CCCCC4

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

42293414

Weight:

1.09 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

P647632-100mg

Country of Origin:

China

CAS:

2173556-69-7

Product Size:

100mg

Harmonized Tariff Code:

2931.90.90