Poly-L-lysine hydrobromide(PDL HBr) (C008B-269921)

Poly-L-lysine (PLL) is a versatile synthetic polymer derived from lysine. It serves as a positively charged, water-soluble polymer with applications in biology and biomedicine. One prominent role of PLL is in cell culture, where it′s applied to dishes and plates to enhance cell adhesion, particularly for cells with poor attachment capabilities. This is crucial for primary cells and certain cancer cell types. PLL′s positive charge forms a layer that attracts negatively charged molecules on cell surfaces, facilitating adhesion while minimizing cell toxicity compared to standard culture surfaces.Additionally, PLL finds utility in microscopy and neuroscience research. Coated substrates enable cells, tissues, and neurons to adhere to slides and culture dishes, facilitating detailed observations and prolonged studies. PLL eliminates the need for cell-damaging fixatives and allows extended cell and tissue culture. Beyond these applications, PLL is employed in immunochemistry to adhere tissues to slides for staining, drug delivery for encapsulating and delivering drugs, and gene therapy to transport genetic material to target cells. Overall, PLL is regarded as biocompatible, ensuring its safety in diverse biomedical applications and making it a valuable tool in biochemical and biomedical research.

Specifications & Purity: Poly-L-lysine (PLL) is a versatile synthetic polymer derived from lysine. It serves as a positively charged, water-soluble polymer with applications in biology and biomedicine. One prominent role of PLL is in cell culture, where it′s applied to dishes and plates to enhance cell adhesion, particularly for cells with poor attachment capabilities. This is crucial for primary cells and certain cancer cell types. PLL′s positive charge forms a layer that attracts negatively charged molecules on cell surfaces, facilitating adhesion while minimizing cell toxicity compared to standard culture surfaces.Additionally, PLL finds utility in microscopy and neuroscience research. Coated substrates enable cells, tissues, and neurons to adhere to slides and culture dishes, facilitating detailed observations and prolonged studies. PLL eliminates the need for cell-damaging fixatives and allows extended cell and tissue culture. Beyond these applications, PLL is employed in immunochemistry to adhere tissues to slides for staining, drug delivery for encapsulating and delivering drugs, and gene therapy to transport genetic material to target cells. Overall, PLL is regarded as biocompatible, ensuring its safety in diverse biomedical applications and making it a valuable tool in biochemical and biomedical research.

PubChem CID: 72363

Isomeric SMILES: C(CCN)C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)N

Storage Temperature: Protected from light;Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

51142552

Weight:

1.07 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

P1524010-500mg

Country of Origin:

China

CAS:

25988-63-0

Product Size:

500mg

Harmonized Tariff Code:

2931.90.90