CAYMAN CHEMICAL
Ponatinib-1 mg
An orally available inhibitor of native Bcr-Abl tyrosine kinase (IC50 = 0.37 nM) as well as various clinically important mutant forms including Bcr-AblT315I (IC50 = 2 nM) inhibits tumor growth in a Ba/F3 Bcr- AblT315I xenograft model of chronic
Description
An orally available inhibitor of native Bcr-Abl tyrosine kinase (IC50 = 0.37 nM) as well as various clinically important mutant forms including Bcr-AblT315I (IC50 = 2 nM); inhibits tumor growth in a Ba/F3 Bcr- AblT315I xenograft model of chronic myeloid leukemia in mice upon oral dosing at 10-30 mg/kg.
Specifications
- UPC:
- 51202000
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 11494-1
- CAS:
- 943319-70-8
Catalog No.
C003B-360526
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