PREKALLIKREIN ACTIVATOR (C005B-253963)

General description

Prekallikrein activator (PKA), also known as Factor XIIa, activates prekallikrein to kallikrein. Activated kallikrein cleaves kininogens into kinins (e.g., bradykinin) that can result in a loss of blood pressure. PKA is assayed by its ability to activate prekallikrein, which once activated cleaves a synthetic peptide substrate and releases a chromophore that can be measured spectrophotometrically. The amount of PKA is determined by comparison with reference standard material. Prekallikrein Activator USP Reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia

Application

Prekallikrein Activator USP Reference standard, is used to prepare standard solutions for prekallikrein activator assay. Further information is available in chapter, 〈165〉 PREKALLIKREIN ACTIVATO, USP43-NF38 – 6583 of United States Pharmacopeia (USP).

Other Notes

This product is part of the USP Biologics program. It is intended for use as a reference standard in pharmaceutical research and development. This product is for test and assay use only. It is not tested for animal or human consumption, clinical testing, or therapeutic use.

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UPC:

51434004

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

23

Unit of Measurement:

EA

MPN:

1559709-22.5IU

Temperature Control Device:

Yes