ProClin‚Ñ¢ 300

General description

ProClin^™ preservatives are water-soluble preparations of biocides that are generally used to increase the shelf life of reagents. ProClin^™ 300 comprises of 3% of 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) and 2-methyl-4-isothiazloin-3-one (MIT) in a salt-free proprietary glycol containing an alkly carboxylate stabilizer. It has a recommended working pH range as 2.5 - 8.5.

Application

ProClin^™ 300 is suitable for preparation of different buffers like ELISA buffer, sample and substrate dilution buffers for Single-Molecule Arrays (Simoa assay) and Immunoenzymatic assay. Additionally, Proclin^™ may be used in preparing storage buffer to store beads coupled with coronavirus nucleocapsid protein for the serological multiplex assay.

For use in IVD Manufacturing

ProClin^™ biocides preservatives are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin^™ toxicity prevent microorganisms from developing high levels of resistance, making ProClin^™ highly efficient even over extended storage periods of your IVD components.

Biochem/physiol Actions

ProClin^™ products contain active substances like CMIT and MIT which inhibit the Krebs cycle at four different check points, the enzymes pyruvate dehydrogenase, α-ketoglutarate dehydrogenase, succinate dehydrogenase, and NADH dehydrogenase. The inhibition of Krebs cycle leads to effective broad-spectrum biocidal activity against bacteria, fungi, and yeast.

Legal Information

ProClin is a trademark of LANXESS Corp.

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada‚Ä≤s Pest Management Regulatory Agency, Turkey‚Ä≤s Biocidal Products Regulation, Korea‚Ä≤s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

UPC:

51441715

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

50

Unit of Measurement:

ML

WeightUOM:

LB

MPN:

48912U