Proteins

Potent MK2 inhibitor.

Potent MK2 inhibitor.

Potent MK2 inhibitor.

Product Describtion:casein kinase 1ε inhibitor.

Product Describtion:casein kinase 1ε inhibitor.

Product Describtion:casein kinase 1ε inhibitor.

Product Describtion:casein kinase 1ε inhibitor.

Product Describtion:casein kinase 1ε inhibitor.

Potent CK1δ/ε inhibitor.

Potent CK1δ/ε inhibitor.

Potent CK1δ/ε inhibitor.

PF 6274484 is a high affinity, irreversible covalent inhibitor of EGFR kinase with Ki of 0.14 nM. PF 6274484 inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R/T790M in H1975 cells with IC50 of 5.8 nM and 6.6 nM,