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Sigma-Aldrich

PSEUDOMONAS EXOTOXIN A FROM PSEUDOMONAS AERUGINOSA

General description Pseudomonas exotoxin A is secreted by Pseudomonas aeruginosa. It is a member of the family mono-ADP-ribosyltransferases.

Description

General description

Pseudomonas exotoxin A is secreted by Pseudomonas aeruginosa. It is a member of the family mono-ADP-ribosyltransferases.

Biochem/physiol Actions

Pseudomonas exotoxin A functions as an anticancer agent.
It catalyses the transfer of ADP-ribose moiety of NAD+ to the histidine imidazole ring of diphthamide.
Shown to be toxic to animals and to cell lines, and to inhibit protein synthesis via ADP ribosylation of elongation factor 2.

Packaging

Package size based on protein content.

Physical form

Lyophilized powder containing Tris buffer, EDTA, NaCl and lactose

Shipping Information:

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Specifications
UPC:
41120000
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
Yes
Quantity:
1
Unit of Measurement:
MG
MPN:
P0184-.5MG
CAS:
91262-95-2
Controlled Substances and Cyanide:
Yes
Catalog No. C005B-440858
Price: $1,158.21
List Price: $1,286.90
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