CAYMAN CHEMICAL
PTC-124-5 mg
A nonaminoglycoside that has been reported to selectively induce ribosomes to read through premature nonsense stop signals on mRNA, thus allowing the production of full-length, functional proteins (IC50 = 7 nM) 60 mg/kg s.c.
Description
A nonaminoglycoside that has been reported to selectively induce ribosomes to read through premature nonsense stop signals on mRNA, thus allowing the production of full-length, functional proteins (IC50 = 7 nM); 60 mg/kg s.c. injection or 0.3-0.9 mg/ml orally has been shown to restore CFTR protein expression and function in a mouse model of cystic fibrosis caused by nonsense mutations.
Shipping Information:
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Specifications
- UPC:
- 12352204
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No"
- Quantity:
- 1
- Unit of Measurement:
- EA
- WeightUOM:
- LB
- MPN:
- 16758-5
- Model Number:
- C817Y87
- Temperature Control Device:
- Yes
Catalog No.
C003B-119115
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