PTP Inhibitor V, PHPS1 (C007B-412172)

PTP inhibitor V, PHPS1 is a cell-permeable phosphotyrosine analogue, which can be used as a reversible, active site as a target, and a Shp-2 inhibitor that competes with the substrate (IC | 50 | and K | i | = 2.1 and 0.73 µM). PHPS1 inhibits ECPTP, PTP1B, Shp1, Mycobacterium MptpA only at higher concentrations (IC | 50 | 5.4, 19, 30, and 39 µM, respectively), and even almost none against PTPH1, STEP, PTPN7, PTPRK, GLEPP1 or LAR2 active. Concentrations up to 50 µM. PTP inhibitor V, PHPS1 has been shown to inhibit Shp-2-dependent cell signal transduction and tumor cell colony formation. Specification: ≥95% Molecular Formula: C21H15N5O6S Molecular Weight: 465.45 PubChem CID: 3109390 Isomeric SMILES: C1=CC=C(C=C1)N2C(=O)C(=C(N2)C3=CC=C(C=C3)[N+](=O)[O-])N=NC4=CC=C(C=C4)S(=O)(=O)O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/P341018-SCI_8e9339ce8880bbc3718b6822138bf759.pdf

UPC:

12352200

Condition:

New

Weight:

0.96 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

P341018-10mg

CAS:

314291-83-3

Product Size:

10mg

Precautionary Statement Codes:

P264