PTP LYP INHIBITOR 1PC X 5MG (C005B-229804)

General description

A cell-permeable, Au(I)-phosphine complex that acts as selective inhibitor of lymphoid tyrosine phosphatase (LYP) (IC₅₀= 1.5 µM) and has a ~10-fold selectivity for LYP over PTP-PEST, HePTP, and CD45 in both JTAg cells and primary mouse thymocytes.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Karver, M.R., et al. 2009. J. Med. Chem.52, 6912.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Molecular Weight: 495.69. Empirical Formula: C₁₇H₁₄AuClNP. Quality Level: 100. Assay: ≥. 95% (HPLC). form: solid. manufacturer/tradename: Calbiochem^®. . storage condition: OK to freeze. color: white. solubility: DMSO: 50 . mg/mL. shipped in: ambient. storage temp.: −. 20°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.

UPC:

51111665

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

5

Unit of Measurement:

MG

MPN:

540217-5MG