CAYMAN CHEMICAL

Pyripyropene A-250 g

A potent inhibitor of ACAT2 (IC50 = 70 nM) with high selectivity over the ACAT1 isozyme (IC50 > 80 &muM) 10-50 mg/kg per day for 12 weeks lowers plasma and hepatic cholesterol, VLDL, and LDL content in apolipoprotein E-knockout mice.

Description

A potent inhibitor of ACAT2 (IC50 = 70 nM) with high selectivity over the ACAT1 isozyme (IC50 > 80 &muM) 10-50 mg/kg per day for 12 weeks lowers plasma and hepatic cholesterol, VLDL, and LDL content in apolipoprotein E-knockout mice.

Specifications

UPC:

51322804

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

11896-250

CAS:

147444-03-9