CAYMAN CHEMICAL
(R)-Bromoenol lactone-1 mg
The PLAs are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The iPLA2 are a PLA2 subfamily closely associated with the release of arachidonic acid in response to
The PLAs are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The iPLA2 are a PLA2 subfamily closely associated with the release of arachidonic acid in response to physiologic stimuli. (R)-BEL is an irreversible, chiral, mechanism-based inhibitor of iPLA2γ. Unlike (S)-BEL, (R)-BEL does not inhibit iPLA2β except at high doses of 20-30 µM. (R)-BEL inhibits human recombinant iPLA2γ with an IC50 of approximately 0.6 µM.
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- UPC:
- 51322003
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- Yes"
- Quantity:
- 1
- Unit of Measurement:
- EA
- WeightUOM:
- LB
- MPN:
- 10006800-1
- Model Number:
- C836D00
- Temperature Control Device:
- Yes
- CAS:
- 478288-90-3



