(R)-DNMDP (C007B-348161)

(R)-DNMDP is a potent and selective cancer cell cytotoxic agent. (R)-DNMDP, the R-form of DNMDP, binds PDE3A directly. (R)-DNMDP has a 500-fold lower EC 50 compared to the (S)-enantiomer in HeLa cell line.In Vitro(R)-DNMDP (0.1 pM-1 mM; for 48 hours) has a 500-fold lower EC 50 compared to the (S)-enantiomer in HeLa cell line. (S)-DNMDP has non-cytotoxic. Binding of PDE3A to the linker analogue is blocked by both trequinsin and (R)-DNMDP, but not by the (S)-DNMDP. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid. Specification: 0.99 Molecular Formula: C15H20N4O3 Molecular Weight: 304.34 PubChem CID: 7122097 Isomeric SMILES: CCN(CC)C1=C(C=C(C=C1)C2=NNC(=O)C[C@H]2C)[N+](=O)[O-]

UPC:

51111633

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

D646575-100mg

CAS:

1630760-60-9

Product Size:

100mg