(Rac)-Tavapadon (C007B-431192)

(Rac)-Tavapadon ((Rac)-PF-06649751) is a potent and selective noncatechol dopamine D1 receptor agonist. (Rac)-Tavapadon displays potent full agonism in the GS activation assay as well as partial agonism in the β-arrestin2 recruitment assay (GS-cAMP, EC 50 =0.8 nM; β-arrestin2, EC 50 =68 nM). (Rac)-Tavapadon has antiparkinsonian activityIn Vitro(Rac)-Tavapadon ((Rac)-PF-06649751; compound 32) has E MAX s of 118% and 30% in the GS activation assay and the β-arrestin2 recruitment assay. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:D 1 Receptor. Specification: 0.99 Molecular Formula: C19H16F3N3O3 Molecular Weight: 391.34 PubChem CID: 86764100 Isomeric SMILES: CC1=C(C=CC(=C1)OC2=C(C=CC=N2)C(F)(F)F)C3=C(C(=O)NC(=O)N3C)C

UPC:

51392413

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

T651255-100mg

CAS:

1643462-64-9

Product Size:

100mg