Recombinant Human CXADR Protein (C007B-540909)

Protein Function:CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 17 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 9% sequence identity with the corresponding regions of rat, human CXADR. Specification: Animal Free, Carrier Free, ≥95%(SDS-PAGE)

UPC:

41106601

Condition:

New

Weight:

1.09 Ounces

HazmatClass:

No;ManufacturerName=Aladdin Scientific"

WeightUOM:

LB

MPN:

rp183611-50μg

Product Size:

50μg

Controlled Substances and Cyanide:

Yes