Recombinant Human Meprin beta Subunit/MEP1B Protein (C007B-573694)

FunctionMembrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components. Cleaves also the amyloid precursor protein/APP, thereby releasing neurotoxic amyloid beta peptides.

Specifictaions: Animal Free, Carrier Free, Bioactive, ActiBioPure™, ≥95%(SDS-PAGE)

Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/RP148698-SCI_afb802eb57da781d154e5b3b0c342b51.pdf

UPC:

51432501

Condition:

New

Weight:

1.09 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

rp148698-10μg

Product Size:

10μg